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Informe completo: Effectiveness and safety of vitamin B12 tests
Objetivo: To evaluate the benefits and harms associated with vitamin B12 tests (i.e. serum B12, holotranscobalamin [holoTC] and methylmalonic acid [MMA]) in patients with a clinical suspicion of, or at high risk for, vitamin B12 deficiency. In addition, legal, social, ethical and organisational issues associated with vitamin B12 testing were considered.
Recomendaciones: The current evidence does not inform the most appropriate test, or combination of tests to investigate a patient with suspected, or at high risk of, B12 deficiency, nor the utility of such tests on impacting patient-relevant outcomes.
Autoría: Swiss Federal Office of Public Health (FOPH)
Año de publicación: 2021